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pentobarbital will lessen the extent or impact of isavuconazonium sulfate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.pentobarbital will reduce the level or result of alosetron by influencing hepatic enzyme CYP2C9/10 metabolism. Minor/Importance Unknown.pentobarbital will minimize the extent or effect of glecaprevir/pi